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Trusted by generations of students and clinicians, this cornerstone two-volume text maintains its accessible, standard-setting balance between the scientific foundations of signs and symptoms, and the clinical management of the patient. This 20th edition is more relevant--and essential--than ever, with a refreshed, user-friendly design and cutting-edge new content that reflects the latest foundational, human papillomavirus rash description, and clinical insights across the human papillomavirus rash description spectrum of medicine.

Essential for practice and education, the landmark 20th Edition features: -Thoroughly revised content--covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison's.

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Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care.

Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention.

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Harrison's summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system's role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease.

New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine--and contain knowledge-building chapters on increasingly vital, fast-evolving areas of medical science and clinical medicine.

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