Current treatment for advanced HCC includes mainly sorafenib and more recently approved regorafenib and nivolumab, as chemotherapy has shown little benefit.
However, the modest hepatocellular cancer immunotherapy and the low response rate from systemic treatments suggest an increased need for new strategies. Recent scientific advances indicate a potential benefit from immunotherapy in hepatocellular carcinoma, due to its immunogenicity. Several trials have evaluated both immunotherapy as monotherapy and the combination with other targeted systemic treatments or local strategies.
The present article reviews current clinical data regarding the possible role of immunotherapy in HCC management and future directions for clinical research. Global cancer statistics CA Cancer J Clin ; 65 2 : Early detection of liver cancer: diagnosis and management.
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IMMUNOTHERAPY IN ADVANCED HEPATOCELLULAR CANCER
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- Duda's group is focused on studies of tumor interaction with its microenvironment, with the goal of identifying the cellular and molecular mechanisms of: 1 local tumor progression in liver cancers and metastatic tumor progression in other gastrointestinal cancers and in prostate and breast malignanciesand 2 treatment resistance in advanced cancers.
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- Cancerul de san se vindeca
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- Human papillomavirus vaccination cost effective
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