Neuroendocrine cancer metastasis. NEUROENDOCRINE TUMORS: CHOOSING APPROPRIATE IMAGING METHODS | The Medical-Surgical Journal

This article provides an overview of the current state of the imaging modalities used for primary tumor visualization, staging and follow-up.

Criterii de eligibilitate: A. Cancere ale capului şi gâtului tumori ale sferei ORL : a identificarea tumorii primare la pacienţii diagnosticaţi clinic cu adenopatie laterocervicală unică, având examen histopatologic de carcinom scuamos metastatic şi fără detecţie a localizării primare prin alte metode imagistice CT, IRM ; b evaluarea neuroendocrine cancer metastasis la tratament la 3 - 6 luni după radiochimioterapie la pacienţii cu mase tumorale reziduale; c diagnosticul diferenţial al recidivei tumorale suspectate clinic, faţă de efectele locale ale radioterapiei.

Detection of NETs and patient monitoring relies mainly on anatomical imaging such as computed tomography CTmagnetic resonance imaging MRIand ultrasonography US under certain conditions. Molecular imaging techniques in combination with CT or MRI hybrid imaging greatly benefit patient management, including better localization of occult tumors and better staging.

Diagnosis of patients with NETs is a complex process and, it is unlikely that any single diagnostic modality to be effective. Thus, NET diagnosis is a process utilizing a variety of methods including blood, urine and tumor tissue samples in combination with anatomical or hybrid imaging for localization, delineation and staging of the disease.

Diagnostic approach to patients with NETs should focus on including hybrid imaging methods, which might play an important role in the future.

MATERIALS AND METHODS: Imaging studies of 22 patients 12 men, mean age 60 years with histopathologically confirmed diagnosis, evaluated in the authors's neuroendocrine cancer metastasis during the last five years were retrospectively reviewed by two radiologists, with findings being consensually described focusing on changes observed at computed tomography. Only one typical carcinoid presented the characteristic appearance of central endobronchial nodule with distal pulmonary atelectasis, while the others were pulmonary nodules or masses. The atypical carcinoids corresponded to peripheral heterogeneous masses.

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Cancerul metastatic cu punct de plecare neprecizat este in continuare o provocare?

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In cancerul metastatic cu punct de plecare neprecizat, identificarea cancerului primitiv ramane prioritatea absoluta. Examinarea bioptica a oricarui tesut disponibil poate reprezenta cheia diagnostica a unui boli metastatice.

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