Source: Clujul Medical. Jun, Vol. Abstract: Neoadjuvant image-guided therapies comprises all locoregional treatment administred to hepatocellular caricinoma patients in order to maintain eligibility during liver transplantation waiting time: transcatheter arterial chemoembolization TACEselective internal radiation therapy SIRTchemical alcohol injection CAIradio frequency paraziti u crijevima kod djece RFA.
This study was effectuated on a total of 56 patients with liver cirrhosis and HCC, which are waiting on the transplant list. According to imaging appearance, compared with imaging study before treatment, the results were interpreted as such: tumor regression, identical size and tumor progression. The treated HCC nodules were analyzed by pathology at the time of liver transplantation.
The follow up was made clinically, biologically alpha-fetoprotein AFP level, and imaging at one month after treatment and every 3 months after transplantation. The average time between treatments up the transplantation was Residual tumor or tumor progression at index nodule level was proven in 14 patients; 8 patients had new lesions. On pretransplant imaging followup 38 of 68 nodules were stable or in hepatocellular cancer up to date.
Contrast imaging exams have a tendency of underestimating viable tumor fraction of the treated lesions and can omit new tumor sites. Neoadjuvant therapy are palliative unable to provide a cure for HCC.
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They are useful by improving outcomes and represents a bridge to liver transplantation. Copyright of Clujul Medical is the property of Cluj Medical University and hepatocellular cancer up to date content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission.
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This volume also provides an up-to-date guide for treatment that explores not only traditional treatments, but newer investigational treatment options including surgical resection, liver transplantation, ablation radiofrequency, microwavepercutaneous ethanol or acetic acid injection, transarterial chemoembolization TACEintra-arterial radiation therapy, and systemic chemotherapy. Heptocellular Carcinoma: Targeted Therapy will be of great value to all health care professionals and trainees worldwide who have an interest in the diagnosis and treatment of HCC, including surgeons, medical oncologists, radiologists, radiation oncologists, and pathologists.
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