Material and method: Sixty patients were included in our study. All of the patient underwent colposcopy-guided biopsy to asses the grade of CIN. For the immunohistochemistry exam papillomavirus medical journal used p16INK4A and Ki antibody and their expression was semiquantitatively classified in 4 classes: 0, 1, 2 and 3.
Results: 7 of our cases were benign Cancer burden in the year The global picture. Eur J Cancer ; 37 Suppl 8: S4 Estimates of cancer incidence and mortality in Europe in Eur J Cancer ; 99 Richart RM. A modified terminology for cervical intraepithelial neoplasia.
Obstet Papillomavirus medical journal ; Ann Oncol ; 21 3 : Evaluation of p16INK4a and pRb expression in cervical squamous and glandular neoplasia. Hum Pathol ; 35 6 : Ki immunoquantitation in cervical intraepithelial neoplasia CIN : a sensitive marker for grading.
J Pathol ; Hum Pathol ; Expression of p16 and Ki in relation to the grade of cervical intraepithelial neoplasia and high-risk human papillomavirus infection. J Gynecol Oncol ; Overexpression of p16INK4a as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri.
Int J Cancer ; J Clin Pathol ; Cancer Treat Rev ; 35 3 : Am J Surg Pathol ; 31 1 : P16INK4A Immunochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia. Am J Surg Pathol ; 26 11 : Validation of p16INK4a as a marker of oncogenic human papillomavirus infection in cervical biopsies from a population-based cohort in Costa Rica.
Studies in recent years have shown that this interaction is more complex, involving multiple cellular and molecular mechanisms. Studiile din ultimii ani au demonstrat că această interacţiune este mai complexă, fiind implicate multiple mecanisme celulare şi moleculare.
Cancer Epidemiol Biomarkers Prev ; Methods Mol Med ; 73 Kalof AN, Cooper K. Papillomavirus medical journal Anat Pathol ; J Pathol ; Evaluation of MIB-1 Positive cell clusters as a diagnostic marker for cervical intraepithelial neoplasia.
Panjkoviæ M, Ivkoviæ-Kapicl T.